Claim 1: a compound of the formula (1), where n represents 1 or 2； X represents - N - O - N - (OR)； r u00b9 represents Hydrogen or Halogen； R u00b2 represents Hydrogen or Methyl； and r u00b3 represents: aryl alkyl c u2081 u208b u2083, which is in the Mono alkyl, optionally substituted with Hydroxy Or heterociclilo； and which is in the aryl mono -, di - or tri substituted- Where the substituents are selected independently from the group consisting of c u2081 u208b u2084 alquenilo c u2082 u208b u2084, alkyl, cycloalkyl c u2083 u208b u2086 c u2081 u208b u2084 alkoxy alkyl, Hydroxy, alkoxy c u2082 u208b u2083 c u2081 u208b u2083, Hydroxy, alkoxy alkyl c u2081 u208b u2082 c u2082 u208b u2083 Hydroxy, alkoxy c u2081 u208b u2082 alq Uilo c u2081 u208b u2082, fluoroalquilo c u2081 u208b u2083, fluoroalcoxi c u2081 u208b u2083, cyano, halogen and c u2081 u208b u2083 heteroaryl alkyl phenoxy； or,Which is in the heterociclilo mono - alkyl substituted； and which is in part heteroaryl mono -, di - or tri - substituted - Where the substituents are selected independently from the group consisting of c u2081 u208b u2084 c u2083 u208b u2086 alkoxy alkyl, cycloalkyl, c u2081 u208b u2084, fluoro C u2081 u208b u2083 Halogen or alkyl and cycloalkyl c u2083 u208b u2087；, which is replaced with mono -, - C (o) or a nh u2082 phenyl optionally mono -,Di - or tri substituted, where the substituents are selected from Halogen, which is c u2085 u208b u2087 or cycloalkyl, optionally substituted mono - or Hydroxy and oxo； which is hybridized with a phenyl optionally mono -, di - or tri substituted, where the substituents are selected from Halogen Cicloalquil c u2083 u208b u2087 alkyl c u2081 u208b u2083； or,In the part which is optionally substituted with Hydroxy alkyl mono -； and which is in the di substituted cycloalkyl optionally with Halogen and optionally substituted with Hydroxy mono -, aryl or heteroaryl, aryl or heteroaryl groups which are optionally mono -, di - or tr I - replaced with H
