A refillable toothbrush and base assembly having a handle assembly, a hinge assembly, a head assembly, brush assembly, a toothpaste cartridge assembly, and a base assembly. The brush assembly is removably mounted to the head assembly. When not in use, the refillable toothbrush assembly rests on the base. A hinge assembly is integrally mounted to the handle assembly. The toothpaste cartridge assembly includes a toothpaste cartridge with an end cap, a plunger and a plunger actuator having a knob. The brush assembly has an internal channel. Upon the rotation of the knob, the toothpaste is forced to travels through the toothpaste cartridge assembly to exit at the brush. A user may rotate the head assembly, with the brush assembly mounted thereto, to a position where the brush assembly is housed within a channel and a cavity disposed at the handle assembly.