NIELSEN PETER KRESTEN,HUBALEK FRANTISEK,LAUTRUP-LARSEN INGER,LUDVIGSEN SVEND,RIBEL-MADSEN ULLA,BALSCHMIDT PER,NØRGAARD PER,HAVELUND SVEND,BALSCHMIDT
申请号：
PL07820423
公开号：
PL2074141T3
申请日:
2007.09.20
申请国别(地区):
PL
年份:
2017
代理人:
摘要：
The present invention relates to novel insulin analogues exhibiting resistance towards protease, wherein at least two amino acids are substituted and/or deleted relative to the parent insulin molecule. A method for the preparation of such insulin analogues, insulin preparations containing the insulin analogues of the invention and a method of treating diabetes mellitus using these insulin analogues is also provided.
