VAN DER PLAS, STEVEN EMIEL,MAMMOLITI, OSCAR,MARTINA, SEBASTIEN LAURENT XAVIER,CLAES, PIETER ISABELLE ROGER,COTI, GHJUVANNI PETRU DIUNISU,ANNOOT, DENIS MAURICE,LOPEZ RAMOS, MIRIAM,GALIEN, RENE ALEXANDR
申请号:
CA3079449
公开号:
CA3079449A1
申请日:
2018.10.11
申请国别(地区):
CA
年份:
2019
代理人:
摘要:
The present invention discloses compounds according to Formula I: (Formula I) Wherein R1, L1, R2, L2, R3, Cy, and the subscript n are as defined herein. The present invention relates to compounds, methods for their production, pharmaceutical compositions comprising the same, and methods of treatment using the same, for the prophylaxis and/or treatment of allergic diseases, inflammatory diseases, metabolic diseases, autoinflammatory diseases, autoimmune diseases, proliferative diseases, transplantation rejection, diseases involving impairment of cartilage turnover, congenital cartilage malformations, and/or diseases associated with hypersecretion of IFNa, IL12 and/or IL23 by administering the compound of the invention.