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METHODS AND COMPOSITIONS FOR MODULATING VOLTAGE-GATED CALCIUM CHANNEL FUNCTION
专利权人:
发明人:
申请号:
EP12821707.2
公开号:
EP2723382A1
申请日:
2012.08.10
申请国别(地区):
EP
年份:
2014
代理人:
摘要:
Therapeutic agents targeted to voltage gated calcium channels and compositions comprising such therapeutic agents are provided, as is the use of such agents and compositions to modulate the function of haematopoietic cells expressing the voltage gated calcium channel. Also provided are methods of screening for agents that target a given voltage gated calcium channel that are suitable for use as therapeutics to modulate the activity of cells expressing the targeted voltage gated calcium channel. The agent can be, for example, an antibody, an aptamer, a peptide or a small molecule capable of binding to an ectodomain of the target voltage gated calcium channel and thus of modulating the function of the calcium channel.
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中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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