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COMPOSITION D'AGENT PORTEUR DE DISTRIBUTION D'ACIDE NUCLÉIQUE INSTANTANÉ
专利权人:
OTSUKA PHARMACEUTICAL CO., LTD.;TAKEUCHI, HIROFUMI
发明人:
申请号:
EP08738918.5
公开号:
EP2140870B1
申请日:
2008.03.26
申请国别(地区):
EP
年份:
2015
代理人:
摘要:
An object of the present invention is to provide a carrier composition for nucleic acid delivery, which can efficiently deliver a nucleic acid into cells when a nucleic acid such as siRNA is administered to animal-derived cells or animals, and also has low toxicity and high safety, and a composition for nucleic acid delivery containing the carrier composition and nucleic acid. A carrier for nucleic acid delivery is prepared by using (A) a diacylphosphatidylcholine, (B) at least one member selected from the group consisting of cholesterol and derivatives thereof, and (C) an aliphatic primary amine. Also, a composition for nucleic acid delivery is prepared by mixing the carrier for nucleic acid delivery with a nucleic acid.
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中国工程科技知识中心
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