Antimicrobial peptides and their use for the treatment of topical infections

• 收藏
• 分享

专利权人:

USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR, V.V.I.;FYZIOLOGICKY USTAV AV CR, V.V.I.

发明人:

Vaclav Cerovsky,Ondrej Nesuta,Vlasta Dudkova,Hana Sychrova,Marie Kodedova

申请号：

US15564035

公开号：

US10160785B2

申请日:

2016.04.08

申请国别(地区):

US

年份:

2018

代理人:

摘要：

Synthetic analogs of general formula (I-A),(I-A)a-Ile-b-c-d-e-f-Lys-Lys-g-h-i-j-Ile-k-Lys-NH2where a is Gly, Lys or β-Ala； b is Met, Leu, Nle, Ile, Trp, Val or Phe； c is Ser, Lys, Arg or Orn； d is Ser, Lys, Arg or Orn； e is Leu, Nle, Ile, Trp, Val or Phe； f is Met, Leu, Nle, Ile, Trp, Val or Phe； g is Leu, Nle, Ile or Trp； h is Lys, Arg, Orn or Ala； i is Lys, Arg, Orn or Ala； j is Ile, Leu, Nle or His； k is Lys, Arg, Orn or Ala； where amino acids in all positions may be in D-configuration, and their use for the treatment of topical infections caused by pathogenic bacteria or yeasts.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/