PROBLEM TO BE SOLVED: To provide an agent for prevention and improvement that is useful for the prevention or improvement of an allergic disease caused by at least type I hypersensitivity, comprising bovine colostrum enzyme-treated material, and provide food and drinks and pharmaceuticals comprising the same.SOLUTION: The present invention provides an agent for the prevention and improvement of an allergic disease caused by at least type I hypersensitivity, comprising bovine colostrum enzyme-treated material that is obtained by a production method comprising a step of bringing bovine colostrum into contact with β-galactosidase.SELECTED DRAWING: None【課題】少なくともI型アレルギーに起因するアレルギー疾患の予防または改善に有用な、ウシ初乳酵素処理物を含んでなる予防改善剤、それを含んでなる飲食品および医薬品を提供する。【解決手段】少なくともI型アレルギーに起因するアレルギー疾患の予防改善剤であって、ウシ初乳をβ-ガラクトシダーゼと接触させる工程を含んでなる製造方法により得られるウシ初乳酵素処理物を含んでなる予防改善剤。【選択図】なし