The invention relates to an antimicrobial peptide with heparin bindingactivity, being derived from endogenous mammalian proteins being substantiallyfree from antimicrobial activity selected from the group consisting of lamininisoforms, complement factor C3, histidin rich glycoprotein and kininogen andhaving from 10 to 36 amino acid residues, wherein the antimicrobial peptideconsists of at least four amino acid residues selected from the groupconsisting of K, R and H. The invention also relates to pharmaceuticalcompositions comprising said antimicrobial peptide and use of theantimicrobial peptide and/or antimicrobial/pharmaceutical composition.
