ALEXANDRE JOSEPH BUCKMELTER,BRUCE FOLLOWS,EDWARD L. FRITZEN,GARY GUSTAFSON,JIAN LIN,JUSTIN A. CARAVELLA,MINGHUA WANG,STEPHANOS IOANNIDIS,ZHONGGUO WANG
申请号：
BR112018010216
公开号：
BR112018010216A2
申请日:
2016.11.18
申请国别(地区):
BR
年份:
2018
代理人:
摘要：
The present invention relates to usp1 inhibitors useful in the treatment of cancers, and other usp1-associated diseases and disorders of formula (i), wherein r1, r2, r3, r3 ', r4, r5, x1, x2, x3, x4, and n are described in this document.a presente invenção refere-se a inibidores da usp1 úteis no tratamento de cânceres, e outras doenças e distúrbios associados à usp1, com a fórmula (i), onde r1, r2, r3, r3', r4, r5, x1, x2, x3, x4, e n são descritos neste documento.
