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A METHOD FOR INCREASING THE AQUEOUS SOLUBILITY OF A BISPHOSPHONIC ACID OR A BISPHOSPHONATE
专利权人:
Grünenthal GmbH
发明人:
HANNA, Mazen,SHAN, Ning,CHENEY, Miranda,WEYNA, David
申请号:
EP20160187412
公开号:
EP3158867(B1)
申请日:
2010.07.30
申请国别(地区):
欧洲专利局
年份:
2018
代理人:
摘要:
Novel solution complexes of zoledronic acid are described which give rise to improved properties of zoledronic acid. The invention includes aqueous solution and molecular complexes of zoledronic acid with and optical isomers of asparagine, histidine, arginine and proline as well as pharmaceutical complexes containing them and methods of treatment using them.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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