Robert L. Wong,Hartmut Kupper,Michelle P. Luo,Joachim Sieper,John C. Davis,Desiree Van Der Heijde,Walter P. Maksymowych
申请号:
US15062992
公开号:
US20160251424A1
申请日:
2016.03.07
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The invention provides methods, uses and compositions for the treatment of ankylosing spondylitis (AS). The invention describes methods and uses for treating ankylosing spondylitis, wherein a TNFα inhibitor, such as human TNFα antibody, or antigen-binding portion thereof, is used to reduce signs and symptoms of ankylosing spondylitis in a subject. Also described are methods for determining the efficacy of a TNFα inhibitor for treatment of ankylosing spondylitis in a subject.