A personalized real-time automated cardiovascular monitoring system monitors abnormalities in a patients cardiovascular activity data through the use of individually adjusted electrocardiogram Holter apparatus (Holter/ECG device) that provides an automatic medical diagnosis of cardiac abnormalities and generates abnormality alert signals representative of certain abnormalities in patients cardiac activities. The signals are transmitted using a wireless network to a medical dispatcher center. A response is generated according to the abnormality detected. Individual parameters indicative of patients cardio activities are personalized to allow for adjustments of chronic patients. A base Holter/ECG unit, includes the wireless/electric electrodes and their respective wireless/electric connections, and a Holter/ECG recording unit affixed to the base unit. Automatic real-time medical response may be provided based on automatic cardiac abnormality alert detection from the Holter/ECG data.