#$%^&*AU2020204434A120200723.pdf#####ABSTRACT A light-based method of inducing physiological change, the method comprising the step of shining light from an artificial blue light source into just one eye of a female horse or other animal, each day for at least 6 weeks, causing a substantial suppression of melatonin production sufficient to induce physiological change, the physiological change being advancing a breeding season of the horse or other animal, wherein the treatment regime is at least as effective as maintaining the horse or other animal indoors under barn lighting to advance the breeding season of the horse or other animal.