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Compositions comprising a fatty acid oil mixture and a surfactant, and methods and uses thereof
专利权人:
PRONOVA BIOPHARMA NORGE AS
发明人:
HUSTVEDT SVEIN OLAF,KLAVENESS JO ERIK JOHNSRUD,OLESEN PREBEN HOULBERG,BERGE GUNNAR
申请号:
NZ59520410
公开号:
NZ595204A
申请日:
2010.03.09
申请国别(地区):
NZ
年份:
2014
代理人:
摘要:
Disclosed herein are preconcentrates comprising a fatty acid oil mixture comprising at least 75% eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), by weight of the fatty acid oil mixture, wherein the EPA and DHA are in a form chosen from ethyl ester and triglyceride; and at least one non-ionic surfactant; wherein the preconcentrate does not comprise a pharmaceutically active agent other than the fatty acid oil mixture. The preconcentrates are capable of forming a self-nanoemulsifying drug delivery system, a self-microemulsifying drug delivery system or a self-emulsifying drug delivery system (SNEDDS, SMEDDS or SEDDS) in an aqueous solution. Also disclosed are food supplement preconcentrates comprising the preconcentrate composition.
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