PROBLEM TO BE SOLVED: To provide a device operation system which can easily change a setting of external devices into another setting without bothering a user.SOLUTION: The device operation system includes: at least one sensor 10 arranged in bedding a biological information detection section 30 detecting biological information vibration of biological information of a user 1 on the bedding 11 with the sensor 10 and outputting biological information signals 30a, 30b an object vibration detection section 40 detecting object vibration generated by the user 1 with the sensor 10 and outputting an object vibration detection signal 40a external devices 22, 23, 24 related to the user 1 and an external device control section 70 controlling the external devices on the basis of the biological information signal 30b and object vibration detection signal 40a.SELECTED DRAWING: Figure 1COPYRIGHT: (C)2016,JPO&INPIT