WEI, YANG,OKAMOTO, HARUKA,GROMADA, JESPER,DAVIS, SAMUEL,MURPHY, ANDREW J.
申请号：
CA3073964
公开号：
CA3073964A1
申请日:
2018.09.21
申请国别(地区):
CA
年份:
2019
代理人:
摘要：
The present invention provides modified glucagon-like peptide 1 (GLP1) polypeptides, fusion proteins comprising modified GLP1 polypeptides, and methods of use thereof. In various embodiments of the invention, the fusion proteins are GLP1 receptor agonists that comprise a modified GLP1 fused to a stabilizing domain. In some embodiments, the fusion proteins comprising modified GLP1 are useful for treating or ameliorating a symptom or indication of a disorder such as obesity and diabetes.
