Helene Rey,Olaf Mundszinger,Isabelle Golfier,Silvia Jakob,Oliver Rusch
申请号：
US14828043
公开号：
US20160256453A1
申请日:
2015.08.17
申请国别(地区):
US
年份:
2016
代理人:
摘要：
The present invention relates to a pharmaceutical composition comprising an opioid receptor antagonist, or a derivative or a pharmaceutically acceptable salt thereof, as an active substance, wherein the composition releases the active substance in a prolonged manner. The composition that is suitable for an administration period of at least twelve-hours for the treatment of severe opioid-induced constipation in patients receiving a daily dosage of opioid equivalent to at least 80 mg of morphine.
