Barbara Wagner,Reinhold Öhrlein,Bernd Herzog,Kai Eichin,Gabriele Baisch,Stephanie Portmann
申请号：
US13000163
公开号：
US09707417B2
申请日:
2009.06.18
申请国别(地区):
US
年份:
2017
代理人:
摘要：
Described is the use of benzotropolone and their derivatives, especially the compounds of formula (1)； wherein R2, R3, R4, R5 and R6 independently of one another are hydrogen； OH； C1-C30alkyl, C2-C30al-kenyl, C1-C30alkoxy, C3-C12cycloalkyl or C1C30hydroxyalkyl, which may be substituted by one or more E and/or interrupted by one or more D； C6-C20aryl, which may be substituted by one or more G； C4-C20heteroaryl, which may be substituted by one or more G, C2-C18alkenyl, C2-C18alkynyl, C7-C25aralkyl, CN, or —CO—R17； C1-C30mono- or dialkylamino； COR9； COOR9； CONR9R10； CN； SO2R9； OCOOR9； OCOR9； NHCOOR9； NR9COR10； NH2； *—(CO)—NH—(CH2)n1—(PO)—(OR11)2； —(CO)—O—(CH2)n1—(PO)—(OR11)2； sulphate； sulphonate； phosphate； phosphonate； —(CH2)n2—[O—(SO2)]n3—OR11； —O—(CH2)n4(CO)n5—R11； —(O)n6—(CH2)n7—(PO)—(OR9)2； —(O)n6—(CH2)n7—SO2—OR9； halogen； organosilanyl； organo-siloxanyl； or a sugar residue linked directly in an α- or β-mode via the anomeric oxygen to the benzotropolone system or via a linear or branched alkylene, alkenylene, alkadiene or alkatriene spacer (sugar-(CH2)n—(X1)1 or 0-benzotropolone system, wherein n=1-10 and X1═—O—； —(CO)—； —O—CO—； —COO—, —NH—； —S—； —SO2—)； R1, R7 and R8 independently of one another are hydrogen； C1C12alkyl or C3-C12-cycloalkyl, which may be substituted by one or more E and/or interrupted by one or more D； C6-C20aryl, which may be substituted by one or more G； C4-C20heteroaryl, which may be substituted by one or more G, C2-C18alkenyl, C2-C18alkynyl, C7-C25aralkyl, or COOR9； COR9； CONR9R10； SO3R9； SO2R9； PO3(R9)2； PO2(R9)2； organosilanyl； organosiloxanyl； or a sugar residue linked directly in an α- or β-mode via the anomeric oxygen to the benzotropolone system or via a linear or branched alkylene, alkenylene, alkadiene or alkatriene spacer (sugar-(CH2)n—(X2)1 or 0—*, wherein n=1-10 and X2═—C(═O)—； —O—CO—*)； R9 and R10 independently from each other are hydrogen； C1C18alkyl or C3-C12-cycloalkyl which may be substituted by one or more E and/or interrupt
