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IL-31 MONOCLONAL ANTIBODIES
专利权人:
发明人:
Anthony W. Siadak,Shirley A. Rene
申请号:
US14498058
公开号:
US20150037331A1
申请日:
2014.09.26
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The present invention relates to methods of treating pruritic diseases, including but not limited to Contact dermatitis, Atopic Dermatitis, Drug induced delayed type cutaneous allergic reactions, Toxic epidermal necrolysis, Cutaneous T cell Lymphoma, Bullous pemphigoid, Alopecia wereata, Vitiligo, Acne Rosacea, Prurigo nodularis, Scleroderma, Herpes simplex virus, or combination thereof by administering IL-31 monoclonal antibodies. The invention provides the hybridomas that generate the monoclonal antibodies and the amino acid sequences of the variable regions of the monoclonal antibodies and chimeric antibodies comprising the amino acid sequences of the light and heavy chain variable regions.
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