Postech Academy-Industry Foundation;Institute for Basic Science
发明人:
Surh, Charles D.,Lee, Jun-Young
申请号:
AU2018271751
公开号:
AU2018271751A1
申请日:
2018.05.25
申请国别(地区):
AU
年份:
2019
代理人:
摘要:
The present invention relates to an antibody that binds to human interleukin-2 (hIL-2), and more particularly to an anti-hIL-2 antibody that binds specifically to a particular epitope of hIL-2, thereby inhibiting the binding of the hIL-2 to CD25. The anti-hIL-2 antibody of the present invention binds specifically to a particular epitope of hIL-2, thereby inhibiting the binding of the hIL-2 to CD25, thereby minimizing expansion of Treg cells. In addition, it stimulates the CD8