Richard Wooster,Sudhakar Kadiyala,Mark T. Bilodeau
申请号:
US16075292
公开号:
US20190365913A1
申请日:
2017.02.03
申请国别(地区):
US
年份:
2019
代理人:
摘要:
Conjugates of an active agent such as a therapeutic, prophylactic, or diagnostic agent attached to a targeting moiety via a linker, and particles comprising such conjugates have been designed which can provide improved temporospatial delivery of the active agent and/or improved biodistribution. Methods of making the conjugates, the particles, and the formulations thereof are provided. Methods of administering the formulations to a subject in need thereof are provided, for example, to treat or prevent cancer or infectious diseases.