FGF受容体活性化N−硫酸塩オリゴ糖、該オリゴ糖の調製および該オリゴ糖の治療用途
- 专利权人:
- 发明人:
- 申请号:
- JP20120524264
- 公开号:
- JP5732460(B2)
- 申请日:
- 2010.08.12
- 申请国别(地区):
- 日本
- 年份:
- 2015
- 代理人:
- 摘要:
The invention relates to FGF receptor-activating N-sulfate oligosaccharides having Formula (I), wherein R1, R4, R6, and R8 are—OSO3−or hydroxyl groups, R2 is an—O-alkyl group or a monosaccharide having Formula (II), R3 is a disaccharide having Formula (III), R5 is a disaccharide having Formula (IV), R7 is a hydroxyl group or a disaccharide having Formula (VI), and R9 is a hydroxyl or—O-alkyl group or a disaccharide having Formula (VII), where R10- is an—O-alkyl group. The invention further relates to the preparation of said oligosaccharides and to the therapeutic use thereof.
- 来源网站:
- 中国工程科技知识中心