The invention relates to selective oestrogen receptor modulators (SERM) and methods of production thereof, use thereof for the treatment and/or prophylaxis of diseases and use thereof for the production of medicinal products for the treatment and/or prophylaxis of diseases, in particular of bleeding disorders, osteoporosis, endometriosis, myomata, hormone-dependent tumours, for hormone replacement therapy and for contraception.本發明係關於選擇性雌激素受體調節劑(SERM)及其製備方法,其於治療及/或預防疾病上之用途,及其於製備供治療及/或預防疾病(尤其出血病症、骨質疏鬆症、子宮內膜異位、肌瘤、激素依賴性腫瘤)、激素替代療法及避孕之藥物上之用途。