Barbara BAUDNER,Derek OHAGAN,Manmohan SINGH,Simone BUFALI
申请号：
US16036487
公开号：
US20180318410A1
申请日:
2018.07.16
申请国别(地区):
US
年份:
2018
代理人:
摘要：
Serogroup B meningococcus antigens can successfully be combined with diphtheria, tetanus and pertussis toxoids (“DTP”) to provide effective combination vaccines for protecting against multiple pathogens. These combinations are effective with a range of different adjuvants, and with both pediatric-type and booster-type DTP ratios. The adjuvant can improve the immune response which the composition elicits alternatively, by including an adjuvant it is possible for the compositions to have a relatively lower amount of antigen while nevertheless having immunogenicity which is comparable to unadjuvanted combination vaccines.
