RUBINO, JOSEPH T.,SISKAVICH, VICTORIA,HARRISON, MAUREEN M.,GANDHI, POOJA
申请号:
CA2493878
公开号:
CA2493878C
申请日:
2003.07.25
申请国别(地区):
CA
年份:
2013
代理人:
摘要:
This invention provides cosolvent concentrates containing rapamycin 42-esterwith3-hydroxy-2-(hydroxymethyl)-2-methylpropionic acid (CCI-779), a parenterallyacceptablesolvent, and an antioxidant. Also provided are parenteral formulations whichcontainaforementioned concentrate, diluent solvent, and a surfactant and methods forpreparing thesame.