Combination Therapies and Uses for Treatment of Demyelinating Disorders

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专利权人:

Biogen MA Inc.

发明人:

Cadavid, Diego,Mi, Sha

申请号：

AU2018203688

公开号：

AU2018203688A1

申请日:

2018.05.25

申请国别(地区):

AU

年份:

2018

代理人:

摘要：

#$%^&*AU2018203688A120180614.pdf#####ABSTRACT Methods and compositions for enhancing one or more of: myelination, re-myelination, oligodendrocyte numbers, or neuroaxonal protection, while ameliorating an inflammatory condition in a human subject are disclosed. In certain embodiments, the methods and compositions described herein include a reparative agent (e.g., a LINGO-I antagonist) and an immunomodulatory agent, in combination. Thus, methods, compositions and kits described herein can be useful for treating a CNS demyelinating disease.

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