This disclosure teaches phospholipid nanoparticle compositions of cannabinoidsformed fromphospholipids and simpler lipids in an unfired sequential process thatencapsulate a highconcentration of cannabinoids, and create standardized precision-metereddosage forms ofcannabinoids； yielding an increase cannabinoid transport across hydrophobicmucosa； increasethe bioavailability of the cannabinoid 2-fold to 8-fold, decrease the dose ofcannabinoids 2-foldto 8-fold less than an amount of cannabinoids needed to illicit the sametherapeutic effectcompared to raw and non-encapsulated cannabinoids； where the nanoparticledynamic structurereduces the adverse effects of cannabinoids； and enable safe more efficaciouscannabinoidtherapy.
