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Pyrazolo [1,5-alpha] pyrimidinyl derivatives useful as corticotropin-releasing factor (CRF) receptor antagonists
专利权人:
Neurocrine Biosciences Inc.;SmithKline Beecham (Cork) Limited
发明人:
Moorjani, Manisha,Lanier, Marion,Williams, John P.,Tellew, John Edward,Zhang, Xiaohu,Luo, Zhiyong
申请号:
AU2005295353
公开号:
AU2005295353B2
申请日:
2005.10.19
申请国别(地区):
AU
年份:
2012
代理人:
摘要:
CRF receptor antagonists are disclosed which may have utility in the treatmentof a variety of disorders, including the treatment of disorders manifestinghypersecretion of CRF in mammals. The CRF receptor antagonists of this inventionhave the following structure: (I); and pharmaceutically acceptable salts,esters, solvates, stereoisomers and prodrugs thereof, wherein R,R, R, Y, Het, , o, R, Ar and Rare as defined herein. Compositions containing a CRF receptor antagonist incombination with a pharmaceutically acceptable carrier are also disclosed,as well as methods for use of the same.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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