POUDRE SECHE POUR PREPARATION A INHALER COMPRENANT DU XINAFOATE DE SALMETEROL, DU PROPIONATE DE FLUTICASONE ET DU BROMURE DE TIOTROPIUM, ET PROCEDE DE PREPARATION ASSOCIE
KIM, KYEONG SOO,LEE, DEOKKYU,KIM, DONG HO,KIM, YONG IL,PARK, JAE HYUN,WOO, JONG SOO
申请号:
CA2876283
公开号:
CA2876283A1
申请日:
2013.06.03
申请国别(地区):
CA
年份:
2013
代理人:
摘要:
Provided is a dry powder for inhalation formulation comprising salmeterol xinafoate, fluticasone propionate and tiotropium bromide, as pharmaceutically active ingredients, and a carrier, and an inhalation formulation comprising same. The inventive dry powder inhalation formulation having good content uniformity and showing small changes in the aerodynamic size distribution in accordance with the flow rate changes can effectively deliver said pharmaceutically active ingredients to a target site upon administration, and thus can be useful in the prevention or treatment of respiratory diseases, particularly asthma and COPD.