THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY
发明人:
SARAGOVI, URI H.,TONG, WENYONG
申请号：
CA2968995
公开号：
CA2968995A1
申请日:
2014.12.04
申请国别(地区):
CA
年份:
2015
代理人:
摘要：
It is provided a multivalent gangloside carbohydrate as a therapeutic cancer vaccine. The GD2 and GD3 carbohydrate conjugated disclosed are linked by a spacer to form a multimer which conserves the native structural feature of naturally occurring GD2 or GD3, the tetramer being immunogenic and elicits cytotoxic anti-gangliosides humoral and cellular responses in vivo.
