The present invention relates to a two-directional tip deflection device for endoscope, comprising a plurality of cylindrical units, a first wire, a second wire, a first flexible unit and a second flexible unit. These wires are passed through holes of cylindrical units. These flexible units are continuously passed through grooves of cylindrical units to form a tubular unit. The tubular unit can be bent by the tension of the first wire or the second wire to control the direction of the endoscope.