PROBLEM TO BE SOLVED: To provide a new preventive or therapeutic agent of diseases caused by IL-6 production.SOLUTION: The preventive and therapeutic agent of diseases caused by production of interleukin-6 contains an antibody (IL-6R antibody) against interleukin-6 receptor, particularly for prevention and treatment of cachexia or anemia. Antibodies of animals such as mouse and rat other than human being, and such as their reconstructed human antibody with a human antibody can be used as the IL-6R antibody.COPYRIGHT: (C)2009,JPO&INPIT【課題】IL-6産生に起因する疾患の新規な予防・治療剤の提供。【解決手段】インターロイキン-6レセプターに対する抗体(IL-6R抗体)を含んで成る、インターロイキン-6の産生に起因する疾患、特に悪液質又は貧血、の予防治療剤。IL-6R抗体としては、マウス、ラット等のヒト以外の動物の抗体、これらとヒト抗体との再構成ヒト抗体等が使用できる。【選択図】なし