AGOURON PHARMACEUTICALS, INC.;CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED
发明人:
WEBBER, STEPHEN EVAN,CANAN-KOCH, STACIE S.,TIKHE, JAYASHREE,THORESEN, LARS HENRIK
申请号:
CA2360003
公开号:
CA2360003C
申请日:
2000.01.10
申请国别(地区):
CA
年份:
2012
代理人:
摘要:
Compounds of formula (I) are poly(ADP-ribosyl)transferase (PARP) inhibitors,and are useful as therapeutics in treatment of cancers and the amelioration ofthe effects of stroke, head trauma, and neurodegenerative disease. As cancertherapeutics, the compounds of the invention may be used, e.g., in combinationwith cytotoxic agents and/or radiation.