[Problem] To provide a vesicle composition having excellent stability over time, and an external skin preparation and a cosmetic, each containing the same.[Solution] [1] A vesicle composition comprising a vesicle having a constituent membrane containing (A) an ether-based nonionic surfactant having a sterol skeleton and (B) a monoalkyl glyceryl ether.[2] An external skin preparation and a cosmetic, each comprising a vesicle composition containing a vesicle having a constituent membrane containing (A) an ether-based nonionic surfactant having a sterol skeleton and (B) a monoalkyl glyceryl ether.
