Component for a malaria vaccine, malaria vaccine, component preparation process, component use, and method of treating a patient susceptible to plasmodium infections
DOMINIQUE INGRID LEMOINE,FLORENCE EMILIE JEANNE FRANCOISE WAUTERS
申请号：
BRPI0822098
公开号：
BRPI0822098A2
申请日:
2008.12.18
申请国别(地区):
BR
年份:
2015
代理人:
摘要：
The present invention relates to a component for a malaria vaccine comprising: a) an immunogenic particle RTS, S and/or b) an immunogenic particle derived from the CS protein of one or more P. vivax strains and S antigen from Hepatitis B and optionally unfused S antigen, or c) an immunogenic particle comprising RTS, CSV-S and optionally unfused S antigen, and d) a stabilizing agent comprising a stabilizing agent with at least one thiol functional group, or mixtures thereof. Methods for preparing the component, its use in medicine, particularly in the prevention of malarial infections, compositions/vaccines containing the component and use of the latter, particularly in therapy are also disclosed.
