An object of the present invention is to provide a medicine supply apparatus including a hopper in which medicine is not likely to remain. The medicine supply apparatus of the present invention includes a hopper and a deforming operation portion. A part of a lower portion of the hopper is configured as a deformable portion having flexibility. The deformable portion is deformable so as to open and close a passage. The deforming operation portion deforms the deformable portion to thereby open and close the passage, and applies vibrations to the deformable portion. The medicine adhering to an inner surface of the deformable portion is processed by the vibrations.