Sensor wire assembly for measuring a physiological variable in a body, said assembly comprises a sensor element for measuring the physiological variable and to generate a sensor signal in response of said variable, and a guide wire having said sensor element at its distal end, and adapted to be inserted into the body in order to position the sensor element within the body. The assembly further comprises a sensor signal adapting circuitry, being an integrated part of said assembly, wherein the sensor signal is applied to the adapting circuitry that is adapted to automatically generate an output signal, related to the sensor signal, in a standardized format such that the measured physiological variable is retrievable by an external physiology monitor.