Jung Sun Yum,Byung Cheol Ahn,Hyun Jin Jo,Dong Yeon Kim,Joo Youn Lee,Ki Hyun Kim,Jae Seung Yoon,Hong Mo Moon
申请号：
US12225341
公开号：
US08216589B2
申请日:
2008.01.28
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The present invention relates to an HBV vaccine comprising an entire hepatitis B surface antigen of L protein, M protein and S protein, in which the produced antigens form virus-like particles, and a multi-antigen vaccine further comprising an HBV core antigen in addition to the entire surface antigen, and a method for preparing the same. The vaccines provide various epitopes and have excellent immunogenicity to induce a strong humoral immune response as well as a cell-mediated immune response.
