Mayo Foundation for Medical Education and Research
发明人:
Allan B. Dietz,William A. Faubion,Eric J. Dozois
申请号:
US16494900
公开号:
US20200093960A1
申请日:
2018.03.21
申请国别(地区):
US
年份:
2020
代理人:
摘要:
This document provides methods and materials for treating fistulas (e.g., refractory fistulas such as refractory anal fistulas). For example, methods and materials for implanting a synthetic scaffold (e.g., fistula plug) comprising randomly arranged fibers comprising polymers of PGA and TMC and seeded with mesenchymal stem cells (e.g., adipose derived mesenchymal stem cells) located in the spaces between the randomly arranged fibers into a fistula (e.g., refractory anal fistula) of a mammal (e.g., a human) are provided.