DING, ZHONGLI,CHEN, GUOHUA,SHASTRY, ASHUTOSH,WORSHAM, ROBERT WADE,SINGH, PARMINDER
申请号:
CA2896188
公开号:
CA2896188A1
申请日:
2013.12.20
申请国别(地区):
CA
年份:
2014
代理人:
摘要:
Microstructure arrays and methods for manufacturing microstructure arrays (10). The microstructure apparatus comprising: a backing (18) having a first surface (20) and a second surface (22) opposed thereto; a microstructure array comprising a plurality of microstructures (12) extending outwardly from the first surface of the backing; the microstructures comprising a biodegradable distal layer (14) and at least one proximal layer (16) positioned between the distal layer and the first surface of the backing; the distal layer comprised of at least one therapeutic agent and at least one polymer; and wherein at least a portion of the distal layer detaches readily upon insertion of the array into skin.