United States Government as Represented by the Department of Veterans Affairs;The Trustees of Indiana University
发明人:
Stephen B. Trippel,Shuiliang Shi
申请号：
US14294305
公开号：
US10434188B1
申请日:
2014.06.03
申请国别(地区):
US
年份:
2019
代理人:
摘要：
The present invention provides fusion proteins including a hyaluronic acid-binding domain of a cartilage matrix protein and a conserved region of a growth factor protein. Certain embodiments provide nucleic nucleic acid sequences encoding a fusion protein and compositions thereof. Methods for using fusion polypeptides and nucleic acid molecules discloses herein are also provided. In certain embodiments, the fusion proteins and/or nucleic acid molecules can be used to treat a cartilage matrix protein-related condition in a subject.
