To provide a culture method of Cordyceps militaris, an extraction method of bioactive substance from a cultured product thereof and a type of activity of the substance, and a composition containing the cultured product or an extract from the cultured product, and also a composition showing erythropoietin inductive action which is useful in preventing or treating anemia which is particularly renal anemia.SOLUTION: Cordyceps militaris mycelium is cultured in solid culture medium or liquid culture medium to obtain a cultured product, and a composition showing erythropoietin inductive action is produced by using the cultured product itself or an extract from the cultured product. The composition is ingested for preventing or treating anemia.SELECTED DRAWING: Figure 5【課題】 サナギタケ(Cordyceps militaris)の培養方法、その培養物からの生理活性物質の抽出方法及び活性の種類、並びにその培養物又はその培養物からの抽出物を含有する組成物を提供すること。貧血、特に腎性貧血の予防又は治療に有用な、エリスロポエチン誘導作用を示す組成物を提供すること。【解決手段】 サナギタケ菌糸体を固体培地又は液体培地で培養し、培養物を得、その培養物そのもの又はその培養物からの抽出物を使用して、エリスロポエチン誘導作用を示す組成物を製造する。貧血の予防又は治療のために、この組成物を摂取させる。【選択図】 図5