Stuart Emanuel,Linda Engle,Ray Camphausen,Martin C. Wright,Ginger Chao Rakestraw,Marco Gottardis,Joan Carboni
申请号：
US13692555
公开号：
US09017655B2
申请日:
2012.12.03
申请国别(地区):
US
年份:
2015
代理人:
摘要：
The present invention relates to bispecific molecules comprising an EGFR binding domain and a distinct IGFIR binding domain for use in diagnostic, research and therapeutic applications. The invention further relates to cells comprising such proteins, polynucleotide encoding such proteins or fragments thereof, and vectors comprising the polynucleotides encoding the innovative proteins. Exemplary bispecific molecules include antibody-like protein dimers based on the tenth fibronectin type III domain.
