SHANGHAI TISSUE ENGINEERING LIFE SCIENCE CO. LTD.;SHANGHAI 9TH PEOPLE'S HOSPITAL, SHANGHAI JIAOTONGUNIVERSITY SCHOOL OF MEDICINE;CAO, YILIN;LIU, WEI;XU, FENG;DENG, DAN;LI, HONG
发明人:
CAO, YILIN,LIU, WEI,XU, FENG,DENG, DAN,LI, HONG
申请号：
WO2008CN70566
公开号：
WO2009003375(A1)
申请日:
2008.03.24
申请国别(地区):
世界知识产权组织国际局
年份:
2009
代理人:
摘要：
The invention discloses a tissue engineering tendon graft, comprising: (a) pharmaceutically-acceptable biodegradable material; and (b) seed cell, which can be inoculated on the described biodegradable material and is selected from: (i) fibroblast; (ii) adipose derived cell, or (iii) mixture of dermal fibroblast and adipose derived cell according to the ratio of 1:10-10000:1. The graft can be prepared by mixing of seed cell and pharmaceutically-acceptable biodegradable material, obtaining a composition of seed cell and pharmaceutically-acceptable biodegradable material, then culturing the composition in bioreactor in vitro. The graft can be used for effectively repairing the damage of tendon.
