BAMDAD, CYNTHIA,SMAGGHE, BENOIT,CARTER, MARK,STEWART, ANDREW
申请号:
CA2991125
公开号:
CA2991125A1
申请日:
2016.07.01
申请国别(地区):
CA
年份:
2017
代理人:
摘要:
The present application discloses a method for generating human tissues in a non-human animal comprising: (i) generating human naive state stem cells and injecting them into a blastocyst or embryo of a non-human animal such that a chimeric animal is generated; (ii) harvesting human tissues, organs, cells or factors secreted by or made in the human tissues or cells from the chimeric animal; and (iii) transplanting or administering the harvested material into a human resulting in generation of human tissues in a non-human animal.