The particle (12) of the medicine manufacture material, especially, the hard gelatin capsule of the type which possesses with the cover and the substance (3 and 4) which accommodate the micro tablet (12) or the pellet the capsule filling up machine (10) in order to produce (C) opening the capsule (C) first the cover of the capsule after separating (3) and the substance (4), by combining, in order to close retention and to handle the capsule (C) plural slide units in order rotary karuseru which (5) is installed the particle (12) (2) and a rest quantity the substance of the respective capsule (4) in order to fill up inside the particle (12)It has with the expedient (11) in order to supply to karuseru (2). Supply expedient (11) has roller expedient (14), with the roller expedient (14) which, at least is dampened partly in the crowded body of the particle (12) inside one which accommodates the crowded body of the particle (12) hopper (13) and the hopper (13) the plural absorption concave sections (15) in order to release inside the pipe (16) of air of the chain which is installed in karuseru (2) the particle (12) of the number of stipulations which are removed from the hopper (13) at the same time accommodation and retention and next the particle (12) possesses.製薬材料の粒子(12)、特に、マイクロタブレット(12)又はペレットを収容する蓋と本体(3、4)とを有するタイプの硬質ゼラチンカプセル(C)を製造するためのカプセル充填機(10)は、最初にカプセルの蓋(3)と本体(4)とを分離した後に組み合わせることによりカプセル(C)を開いて閉じるためにカプセル(C)を保持及び取扱うための複数のスライドユニット(5)を取付ける回転カルーセル(2)と、一服分量の粒子(12)をそれぞれのカプセルの本体(4)内に充填するために粒子(12)をカルーセル(2)に供給するための手段(11)とを備える。供給手段(11)は、粒子(12)の密集体を収容する少なくとも一つのホッパ(13)と、ホッパ(13)内の粒子(12)の密集体に部分的に浸されるローラ手段(14)とを備え、ローラ手段(14)が、ホッパ(13)から取り出す規定数の粒子(12)を収容及び保持及び且つ次に粒子(12)をカルーセル(2)に取り付けた一続きの中空の導管(16)内に解放するための複数の吸引凹部(15)を有する。
