The present invention relates to a method for detecting leakages in a system for conducting a medical fluid upstream a shut-off device of the system as well as systems related thereto. More specifically, the method is used with systems having a section conducting the medical fluid, the section being arranged upstream the shut-off device, which is configured to interrupt or reduce an escaping or outflow of the fluid out of the section into an area downstream the shut-off device. The system for use with the present method further has at least one conveying device for conveying the fluid through the section. The present invention further relates to a digital storage medium, a computer program product and a computer program for performing the method for detecting leakages.