Teresa Silva Rivera;Angel Concheiro Nine;Ana Rey Rico;José Couceiro Follente;Carmen Alvarez Lorenzo
发明人:
Carmen Alvarez Lorenzo,Ana Rey Rico,Teresa Silva Rivera,José Couceiro Follente,Angel Concheiro Nine
申请号：
US13704986
公开号：
US20130156724A1
申请日:
2011.05.12
申请国别(地区):
US
年份:
2013
代理人:
摘要：
The invention describes for first time the activity of poloxamines as inducers in the differentiation of mesenchymal or progenitor cells. In particular, the invention demonstrates that poloxamines have an osteogenic ability. The invention relates to the use of one or more poloxamines or a pharmaceutical composition comprising same for the preparation of a drug for treting patients with bone defects in general. The invention also relates to a method for inducing the differentiation of mesenchymal or progenitor cells into osteoblasts by bringing said cells into contact with a sterilised aqueous dispersion or solution of one or more poloxamines.
