抗CD73抗體、其抗原結合片段及應用农业专利-农业专业知识服务系统

专利权人:: JIANGSU HENGRUI MEDICINE CO., LTD.;SHANGHAI HENGRUI PHARMACEUTICAL CO., LTD.

发明人:: CAO, ZHUOXIAO,曹卓晓,曹卓曉,FU, YAYUAN,付雅媛,XU, ZHIBIN,许志宾,許志賓,ZHANG, LIMIN,张利敏,張利敏,HU, QIYUE,胡齐悦,胡齊悅,TAO, WEIKANG,陶维康,陶維康

摘要：: The present disclosure relates to anti-CD73 antibodies, antigen-binding fragments thereof and use thereof. Furthermore, the present disclosure discloses a murine, chimeric or humanized anti-CD73 antibody or the antigen binding fragment thereof containing a particular CDR region. The present disclosure further comprises a pharmaceutical composition comprising the anti-CD73 antibody or the antigen binding fragment therefor, and its use as a diagnostic agent and therapeutic drug for CD73 related diseases.本公開涉及抗CD73抗體、其抗原結合片段及應用。具體地，本公開公開包含特定CDR區的鼠源、嵌合或人源化抗CD73抗體及其抗原結合片段。本公開還公開包含所述抗CD73抗體或其抗原結合片段的醫藥組成物，以及其作為CD73相關疾病診斷劑和治療藥物的用途。